What is Inflamm-Ageing?
Scientists are still working to unravel the mysteries of ageing, but one thing they do know for sure -chronic, low-level inflammation plays a big role.1a This slow-burning process, known as inflammaging, gradually affects how our body functions over time.1b And because our skin is the body’s largest organ, inflammation there doesn’t just stay on the surface – it can have widespread effects. We see this in conditions like psoriasis and eczema, where skin inflammation doesn’t just cause discomfort, but it also impacts overall health.1c
What Causes Skin Inflammation?
As we get older, our skin loses its ability to repair and protect itself as efficiently as it once did. This happens because senescent cells (older cells that no longer function properly) start to build up. Instead of helping, they contribute to chronic inflammation and make it harder for the skin to recover from damage.2a Over time, this creates a vicious cycle. Inflammation weakens the skin, which then leads to more inflammation, breaking down essential structural components like collagen and elastin.2b This doesn’t just affect how skin looks – it also impacts the immune system, making it harder for the body to remove damaged cells and fight off irritants.2c
The result? Thinner, weaker skin that is more prone to wrinkles and skin discolouration.3 The good news is that properly caring for your skin with a moisturising cream may lower inflammation levels.4

How E45 Helps Fight Inflamm-Ageing
For over 70 years, E45 has been the expert in caring for dry skin and itchy skin. E45’s lotions, creams, and face care products have been developed for different skin types and different parts of the body. Products work hard to protect and maintain skin health.14
E45 Face Foaming Cleanser5
The E45 Face Foaming Cleanser is a daily face wash specially designed for dry, sensitive, and eczema-prone skin.
E45 Face Daily Protect6
The E45 Daily Protect Moisturiser with SPF 30 is a lightweight face cream that’s perfect for dry, sensitive, and eczema-prone skin.
E45 Face Night Cream7
The E45 Face Night Cream is an overnight moisturiser designed for dry, sensitive, and eczema-prone skin.
E45 Face Hydrating Serum8
A clinically proven triple moisturising complex powers the E45 Hydrating Face Serum which includes hyaluronic acid to deliver intense hydration.
E45 Lips & Dry Skin Balm9
The E45 Lips & Dry Skin Balm is a multi-purpose balm specially designed to care for cracked lips and small dry patches on the hands, face, and body.
E45 Cream10
E45 Cream, with its rich emollient action, is more than just a moisturiser – it’s an intensely hydrating solution for managing a wide range of dry skin conditions, including eczema.
E45 Rich 24-Hour Lotion11
The E45 Rich 24-Hour Lotion delivers long-lasting hydration with a lightweight feel and is designed for dry and sensitive skin and offers deep, nourishing moisturisation that lasts all day, without the heaviness or greasy residue.
E45 Moisturising Lotion12
E45 Moisturising Lotion is a lightweight and easy-to-apply everyday moisturiser designed to soothe and protect dry, sensitive skin.
E45 Daily Lotion13
Fast-absorbing and fuss-free, the E45 Daily Lotion is your go-to for everyday hydration.
Final Thoughts
Inflamm-ageing might be an unavoidable part of ageing, but you can slow down its effects with the right skincare approach. E45’s range provides the hydration, repair, and protection needed to keep your skin youthful and resilient. Embrace a skincare routine that works with your skin, not against it. Embrace E45.

For more information, visit E45 and join the conversations on Facebook, YouTube, Tik Tok and Instagram. E45‘s range of products are available from selected independent pharmacies, Clicks and Dis-Chem stores. The range is also available from Takealot. Keep a look out for the new packaging designs which will be filtering into stores shortly.